Keeton, Adam: search on Z-Library

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1

Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents

Eldehna, Wagdy M., Al-Wabli, Reem I., Almutairi, Maha S., Keeton, Adam B., Piazza, Gary A., Abdel-Aziz, Hatem A., Attia, Mohamed I.

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 2.01 MB

english, 2018

2

Lung Cells from Neonates Show a Mesenchymal Stem Cell Phenotype

Hennrick, Kenneth T., Keeton, Angela G., Nanua, Suparna, Kijek, Theresa G., Goldsmith, Adam M., Sajjan, Umadevi S., Bentley, J. Kelley, Lama, Vibha N., Moore, Bethany B., Schumacher, Robert E., Thanni

Journal:

American Journal of Respiratory and Critical Care Medicine

Year:

2007

Language:

english

File:

PDF, 1.55 MB

english, 2007

3

NSAIDs: Old Drugs Reveal New Anticancer Targets

Piazza, Gary A., Keeton, Adam B., Tinsley, Heather N., Whitt, Jason D., Gary, Bernard D., Mathew, Bini, Singh, Raj, Grizzle, William E., Reynolds, Robert C.

Journal:

Pharmaceuticals

Year:

2010

Language:

english

File:

PDF, 443 KB

english, 2010

4

Insulin-Regulated Expression of Egr-1 and Krox20: Dependence on ERK1/2 and Interaction with p38 and PI3-Kinase Pathways

Keeton, Adam B., Bortoff, Katherine D., Bennett, William L., Franklin, J. Lee, Venable, Derwei Y., Messina, Joseph L.

Journal:

Year:

2003

Language:

english

File:

PDF, 331 KB

english, 2003

5

New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres

Attia, Mohamed I., Eldehna, Wagdy M., Afifi, Samar A., Keeton, Adam B., Piazza, Gary A., Abdel-Aziz, Hatem A., Filleur, Stéphanie

Journal:

Year:

2017

Language:

english

File:

PDF, 3.32 MB

english, 2017

6

PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/Î²-catenin transcription, cancer cell growth, and tumor immunity

Piazza, Gary A., Ward, Antonio, Chen, Xi, Maxuitenko, Yulia, Coley, Alex, Aboelella, Nada S., Buchsbaum, Donald J., Boyd, Michael R., Keeton, Adam B., Zhou, Gang

Journal:

Drug Discovery Today

Year:

2020

File:

PDF, 912 KB

2020

7

Novel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemoprevention

Aboul-Fadl, Tarek, Al-Hamad, Suliman S., Lee, Kevin, Li, Nan, Gary, Bernard D., Keeton, Adam B., Piazza, Gary A., Abdel-Hamid, Mohammed K.

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 3.12 MB

english, 2014

8

Regulation of Gene33 expression by insulin requires MEK–ERK activation

Adam B. Keeton, Jie Xu, J. Lee Franklin, Joseph L. Messina

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2004

Language:

english

File:

PDF, 363 KB

english, 2004

9

Quinazoline and tetrahydropyridothieno[2,3-d]pyrimidine derivatives as irreversible EGFR tyrosine kinase inhibitors: influence of the position 4 substituent

Hamed, Mostafa M., Abou El Ella, Dalal A., Keeton, Adam B., Piazza, Gary A., Engel, Matthias, Hartmann, Rolf W., Abadi, Ashraf H.

Journal:

Year:

2013

Language:

english

File:

PDF, 297 KB

english, 2013

10

The RAS–Effector Interaction as a Drug Target

Keeton, Adam B., Salter, E. Alan, Piazza, Gary A.

Journal:

Cancer Research

Year:

2017

Language:

english

File:

PDF, 279 KB

english, 2017

11

Quantity and dynamics of dead wood in managed and unmanaged dry-mesic oak forests in the Hungarian Carpathians

Bölöni, János, Ódor, Péter, Ádám, Réka, Keeton, William S., Aszalós, Réka

Journal:

Forest Ecology and Management

Year:

2017

Language:

english

File:

PDF, 1.07 MB

english, 2017

12

Insulin regulation of growth hormone receptor gene expression: involvement of both the PI-3 kinase and MEK/ERK signaling pathways

William L. Bennett, Adam B. Keeton, Shaonin Ji, Jie Xu, Joseph L. Messina

Journal:

Endocrine (Springer)

Year:

2007

Language:

english

File:

PDF, 334 KB

english, 2007

13

Synthesis of some dihydropyrimidine-based compounds bearing pyrazoline moiety and evaluation of their antiproliferative activity

Awadallah, Fadi M., Piazza, Gary A., Gary, Bernard D., Keeton, Adam B., Canzoneri, Joshua C.

Journal:

European Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.60 MB

english, 2013

14

Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors

ElHady, Ahmed K., Shih, Shou-Ping, Chen, Yu-Cheng, Liu, Yi-Chang, Ahmed, Nermin S., Keeton, Adam B., Piazza, Gary A., Engel, Matthias, Abadi, Ashraf H., Abdel-Halim, Mohammad

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 3.20 MB

2020

15

Lensing Probabilities for Spectroscopically Selected Galaxy‐Galaxy Strong Lenses

Dobler, Gregory, Keeton, Charles R., Bolton, Adam S., Burles, Scott

Journal:

The Astrophysical Journal

Year:

2008

Language:

english

File:

PDF, 844 KB

english, 2008

16

Metabolism and growth inhibitory activity of cranberry derived flavonoids in bladder cancer cells

Prasain, Jeevan K., Rajbhandari, Rajani, Keeton, Adam B., Piazza, Gary A., Barnes, Stephen

Journal:

Food & Function

Year:

2016

Language:

english

File:

PDF, 942 KB

english, 2016

17

Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins

Almutairi, Maha S., Hassan, Eman S., Keeton, Adam B., Piazza, Gary A., Abdelhameed, Ali S., Attia, Mohamed I.

Journal:

Drug Design Development and Therapy

Year:

2019

Language:

english

File:

PDF, 947 KB

english, 2019

18

Exploiting RAS Nucleotide Cycling as a Strategy for Drugging RAS-Driven Cancers

Mattox, Tyler E., Chen, Xi, Maxuitenko, Yulia Y., Keeton, Adam B., Piazza, Gary A.

Journal:

International Journal of Molecular Sciences

Year:

2019

Language:

english

File:

PDF, 1.02 MB

english, 2019

19

Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors

Abdel-Halim, Mohammad, Tinsley, Heather, Keeton, Adam B., Weam, Mohammed, Atta, Noha H., Hammam, Mennatallah A., Hefnawy, Amr, Hartmann, Rolf W., Engel, Matthias, Piazza, Gary A., Abadi, Ashraf H.

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 921 KB

2020

20

ChemInform Abstract: Synthesis of Novel Tadalafil Analogues and Their Evaluation as Phosphodiesterase Inhibitors and Anticancer Agents.

Ashraf H. Abadi, Dalal A. Abouel-Ella, Nermin S. Ahmed, Bernard D. Gary, Jose T. Thaiparambil, Heather N. Tinsley, Adam B. Keeton, Gary A. Piazza

Journal:

Year:

2009

File:

PDF, 33 KB

2009

21

Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer

Adamska, Aleksandra, Domenichini, Alice, Capone, Emily, Damiani, Verena, Akkaya, Begum Gokcen, Linton, Kenneth J., Di Sebastiano, Pierluigi, Chen, Xi, Keeton, Adam B., Ramirez-Alcantara, Veronica, Max

Journal:

Journal of Experimental & Clinical Cancer Research

Year:

2019

Language:

english

File:

PDF, 2.29 MB

english, 2019

22

Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-growth inhibitors in tumor cells with wild type p53

Abdel-Halim, Mohammad, Keeton, Adam B., Gurpinar, Evrim, Gary, Bernard D., Vogel, Simon M., Engel, Matthias, Piazza, Gary A., Boeckler, Frank M., Hartmann, Rolf W., Abadi, Ashraf H.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 994 KB

english, 2013

23

Blockade of Rapid Versus Prolonged Extracellularly Regulated Kinase 1/2 Activation Has Differential Effects on Insulin-Induced Gene Expression

Keeton, Adam B., Bortoff, Katherine D., Franklin, J. Lee, Messina, Joseph L.

Journal:

Year:

2005

Language:

english

File:

PDF, 462 KB

english, 2005

24

ChemInform Abstract: Synthesis of Some Dihydropyrimidine-Based Compounds Bearing Pyrazoline Moiety and Evaluation of Their Antiproliferative Activity.

Awadallah, Fadi M., Piazza, Gary A., Gary, Bernard D., Keeton, Adam B., Canzoneri, Joshua C.

Journal:

Year:

2014

File:

PDF, 28 KB

2014

25

Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling

Abdel-Aziz, Hatem, Eldehna, Wagdy, Keeton, Adam, Piazza, Gary, Kadi, Adnan, Attwa, Mohamed, Abdelhameed, Ali, Attia, Mohamed

Journal:

Drug Design Development and Therapy

Year:

2017

Language:

english

File:

PDF, 1.19 MB

english, 2017

26

Suppression of Wnt/β-catenin signaling inhibits prostate cancer cell proliferation

Wenyan Lu, Heather N. Tinsley, Adam Keeton, Zhican Qu, Gary A. Piazza, Yonghe Li

Journal:

European Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 715 KB

english, 2009

27

Synthesis and Optimization of New 3,6-Disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex

Rezk, Mohamed Salah, Abdel-Halim, Mohammad, Keeton, Adam, Franklin, Derek, Bauer, Matthias, Boeckler, Frank Michael, Engel, Matthias, Hartmann, Rolf Wolfgang, Zhang, Yanping, Piazza, Gary Anthony, Aba

Year:

2016

Language:

english

File:

PDF, 851 KB

english, 2016

28

Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins

Almutairi, Maha S., Hassan, Eman S., Keeton, Adam B., Piazza, Gary A., Abdelhameed, Ali S., Attia, Mohamed I.

Journal:

Drug Design Development and Therapy

Year:

2019

File:

PDF, 947 KB

2019

29

Mechanisms of Hemorrhage-Induced Hepatic Insulin Resistance: Role of Tumor Necrosis Factor-α

Ma, Yuchen, Toth, Balazs, Keeton, Adam B., Holland, LaWanda T., Chaudry, Irshad H., Messina, Joseph L.

Journal:

Year:

2004

Language:

english

File:

PDF, 352 KB

english, 2004

30

Modulation of Elk-dependent-transcription by Gene33

Adam B. Keeton, Joseph L. Messina

Journal:

Journal of Cellular Biochemistry

Year:

2005

Language:

english

File:

PDF, 209 KB

english, 2005

31

THE DISCOVERY OF THE MOST DISTANT KNOWN TYPE Ia SUPERNOVA AT REDSHIFT 1.914

Jones, David O., Rodney, Steven A., Riess, Adam G., Mobasher, Bahram, Dahlen, Tomas, McCully, Curtis, Frederiksen, Teddy F., Casertano, Stefano, Hjorth, Jens, Keeton, Charles R., Koekemoer, Anton, Str

Journal:

The Astrophysical Journal

Year:

2013

Language:

english

File:

PDF, 1.15 MB

english, 2013

32

Design and synthesis of 1,2,4‐triazolo[1,5‐ a ]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity

Abd El‐Aleam, Rehab H., George, Riham F., Lee, Kevin J., Keeton, Adam B., Piazza, Gary A., Kamel, Amr A., El‐Daly, Mahmoud E., Hassan, Ghaneya S., Abdel‐Rahman, Hamdy M.

Journal:

Archiv der Pharmazie

Year:

2019

Language:

english

File:

PDF, 1.25 MB

english, 2019

33

Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy

Emmanouilidi, Aikaterini, Casari, Ilaria, Gokcen Akkaya, Begum, Maffucci, Tania, Furic, Luc, Guffanti, Federica, Broggini, Massimo, Chen, Xi, Maxuitenko, Yulia Y., Keeton, Adam B., Piazza, Gary A., Li

Journal:

Year:

2020

File:

PDF, 2.66 MB

2020

34

Gene 33 inhibits apoptosis of breast cancer cells and increases poly(ADP-ribose) polymerase expression

Jie Xu, Adam B. Keeton, Liyu Wu, John L. Franklin, Xu Cao, Joseph L. Messina

Journal:

Breast Cancer Research and Treatment

Year:

2005

Language:

english

File:

PDF, 396 KB

english, 2005

35

Synthesis of Novel Tadalafil Analogues and their Evaluation as Phosphodiesterase Inhibitors and Anticancer Agents

Ashraf H, Abadi, Dalal A, Abouel-Ella, Nermin S, Ahmed, Bernard D, Gary, Jose T, Thaiparambil, Heather N, Tinsley, Adam B, Keeton, Gary A, Piazza

Journal:

Arzneimittelforschung

Year:

2011

Language:

english

File:

PDF, 347 KB

english, 2011

36

Targeting cGMP/PKG signaling for the treatment or prevention of colorectal cancer with novel sulindac derivatives lacking cyclooxygenase inhibitory activity

Piazza, Gary A., Chen, Xi, Ward, Antonio, Coley, Alex, Zhou, Gang, Buchsbaum, Donald J., Maxuitenko, Yulia, Keeton, Adam B.

Journal:

Oncology Signaling

Year:

2020

File:

PDF, 579 KB

2020

37

Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS

Ward, Antonio B., Keeton, Adam B., Chen, Xi, Mattox, Tyler E., Coley, Alex B., Maxuitenko, Yulia Y., Buchsbaum, Donald J., Randall, Troy D., Zhou, Gang, Piazza, Gary A.

Journal:

Year:

2020

File:

PDF, 534 KB

2020

38

6-Aryl and Heterocycle Quinazoline Derivatives as Potent EGFR Inhibitors with Improved Activity toward Gefitinib-Sensitive and -Resistant Tumor Cell Lines

Hamed, Mostafa M., Abou El Ella, Dalal A., Keeton, Adam B., Piazza, Gary A., Abadi, Ashraf H., Hartmann, Rolf W., Engel, Matthias

Journal:

Year:

2013

Language:

english

File:

PDF, 719 KB

english, 2013

39

Exploiting RAS Nucleotide Cycling as a Strategy for Drugging RAS-Driven Cancers

Mattox, Tyler E., Chen, Xi, Maxuitenko, Yulia Y., Keeton, Adam B., Piazza, Gary A.

Journal:

International Journal of Molecular Sciences

Year:

2019

File:

PDF, 1.02 MB

2019

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